lab

Why NIAGEN® is worth the hype

How this one exceptional vitamin got the attention of the scientific community.

Studies on our key ingredient have more than doubled since 2014


Over 150 scientific articles have been published on our key ingredient since its discovery in 2004. The number of papers coming out each year is steadily increasing as scientists continue to uncover the potential of this remarkable nutrient. (i)

fbo chart fbo chart

Scientific articles listed under “nicotinamide riboside(NR)” on PubMed

Our Chief Scientific Advisor led the discovery


charles brenner

Charles Brenner, Ph.D.

Our Chief Scientific Advisor led the discovery


In 2004, Dr. Charles Brenner discovered nicotinamide riboside (NR) could increase levels of a vital cellular resource. This resource is a central regulator in energy metabolism and is believed to play an important role in healthy human aging. Although NR is a naturally-occurring vitamin in milk, it’s only found in trace amounts. Based on Dr. Brenner’s patents and the established techniques of our parent company ChromaDex, NR was exclusively licensed and developed as NIAGEN®.

NIAGEN® increases NAD, a vital resource for cellular energy


NAD (or nicotinamide adenine dinucleotide) is a vital resource found in all living cells. We use it every day. After over 100 years of studying this molecule, researchers are publishing more articles about NAD than ever before. Now we know NAD isn’t a constant resource. Things like overeating, staying in the sun too long, or drinking alcohol can stress our system and cause NAD to decline. Some scientists even think this NAD decline plays a major role in how we age.

chart

Massudi, et al., 2012

Based on one analysis of human skin tissue

chart

Martens, et al., 2018

On average at 1000 mg / day for 6 weeks in 21 people

quotation

NIAGEN® has a remarkable ability to boost NAD in tissues that need it.

—Charles Brenner, Ph.D.

quotation

The science speaks for itself


More than 20 human clinical trials on NR are already registered, and more than 100 preclinical studies have already been published.

Human Clinical Studies

  • NIAGEN® safely and effectively increases NAD

    Trammell,et al.,2016

  • NIAGEN® shows promise for supporting cardiovascular health

    Martens, et al., 2018

  • NIAGEN® shows promise for supporting liver health

    Dollerup, et al., 2018

  • NIAGEN® safely and effectively increases NAD

    Trammell, et al., 2016

    NIAGEN® shows promise for supporting cardiovascular health

    Martens, et al., 2018

    NIAGEN® shows promise for supporting liver health

    Dollerup, et al., 2018

    Preclinical Studies

    Preclinical studies are trials conducted in non-human models.

  • NAD & Metabolism

    Canto, et al., 2012

  • NAD & Hearing

    Brown, et al., 2014

  • NAD & Muscles

    Frederick, et al., 2016

  • NAD & The Liver

    Mukherjee, et al., 2016

  • NAD & Aging

    Zhang, et al., 2016

  • NAD & The Heart

    Diguet, et al., 2018

  • NAD & Metabolism

    Canto, et al., 2012

    NAD & Hearing

    Brown, et al., 2014

    NAD & Muscles

    Frederick, et al., 2016

    NAD & The Liver

    Mukherjee, et al., 2016

    NAD & Aging

    Zhang, et al., 2016

    NAD & The Heart

    Diguet, et al., 2018

    NIAGEN® by the numbers


    certificates

    3 FDA Safety Reviews


    customer

    4 Published Human Trials


    license

    20+ Licensed Patents


    partnership

    140+ Research Collaborations

    truniagen bottle

    AGE BETTER®
    LIVE BETTER


    Save up to 40%

    As low as $30 + FREE U.S. shipping