Let’s take a quick look at NAD+ and the role it plays in your body. This information may help you decide which Tru Niagen serving is best for you. 300mg of Niagen, our patented form of nicotinamide riboside (NR), is the minimum amount we recommend. Taking 1,000mg may further increase NAD+ to help address the problems that come with the aging process and/or a stressful lifestyle. Both servings are safe and effective.

What Is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is an essential coenzyme that helps generate energy within a cellular organelle called the mitochondria. Nicknamed the powerhouse of the cell, mitochondria make energy for all of your cellular functions. A full 90% of your energy is produced within the mitochondria with the help of NAD+.

NAD+ and Aging

Not only does NAD+ play a central role in energy production, it also helps support cellular repair throughout the trillions of cells—and organs—in your body. In fact it is essential for the function of all 37.2 trillion cells, promoting survival, repair, and even differentiation of stem cells into organs and tissues.

Unfortunately, NAD+ decreases with age. Research shows that the NAD+ levels in our bodies decline by up to 65% between the ages of 30 and 70. Low levels of NAD+ can lead to mitochondrial inefficiency. This may reduce your cells’ ability to produce the energy they need to carry out their many functions, and can have longer-term health implications.

So if you’re over 40 years old or over 30 with a stressful lifestyle, you might consider an extra NAD+ boost via supplementation with an NAD+ precursor like Tru Niagen.

Age-Related NAD+ Decline and How It Affects Specific Organs and Systems

NAD+ and the brain:

At only 2% of your body weight, the brain’s main function—processing and transmitting information—consumes a full 20% of your body’s energy every day.

The age-related decline in NAD+ can lead to less cellular energy, which can negatively affect neuronal function, and potentially lead to further brain health problems over time.

NAD+ and the heart:

As a hard-working organ, the heart requires a lot of energy to continuously pump blood throughout your entire life. A large part of what fuels the cells in your heart are thousands of mitochondria. As we age and NAD+ levels decrease, mitochondria may not produce energy for the heart to work as efficiently as it did when you were younger.

NAD+ and cellular repair:

Mitochondria are not perfect, and in the making of energy they also make byproducts called free radicals. Free radicals are devastating to cell function. Normally, antioxidants fight free radicals, but certain lifestyle stressors such as drinking, too much sunlight, and poor diet can tip the delicate balance between free radicals and antioxidants, causing oxidative stress. Healthy levels of NAD+ can even the score by limiting free-radical damage. As we age and NAD+ declines, our cells become less efficient in their ability to repair.

NAD+ and the immune system:

Healthy levels of NAD+ are especially important during times of physiological stress. NAD+ can be depleted by up to 80% due to immune health challenges. This can contribute to a lack of cellular resilience.

In short, NAD+ helps power hundreds of energy-demanding metabolic processes. Without NAD+, your heart wouldn’t pump blood. Your lungs wouldn’t pull in air. The neurons in your brain wouldn’t fire. And your cells would not properly repair themselves.

So How Much NAD+ Do You Need?

You can see from the above information that the need for NAD+ varies greatly due to age, lifestyle, exposure to physical stressors, and general health.

Tru Niagen 300mg

300mg is the minimum daily serving we recommend to maintain boosted NAD+ levels. This is a safe and effective dose for those who are in relatively good health and want to safeguard their vitality with early NAD+ support. Taking 300mg daily is proven to increase NAD+ levels by up to 51% in as soon as two weeks.

Our 300mg serving comes in two forms, capsules and Stick Packs, for those who prefer supplements in powder form to drink on the go, or mix into their favorite cold or room temperature beverages.

Tru Niagen 1,000mg

Tru Niagen 1,000mg is for those seeking to reap the benefits of increased NAD+ supplementation at the clinical-strength serving. Studies show that taking 1,000mg daily can increase in NAD+ by up to 150% in 3 weeks. Since NAD+ does decrease quite a bit the older you get, it makes sense to increase supplementation as we age. Especially given the fact that there’s really no feasible way to boost NAD+ sufficiently through diet. Taking 1,000mg is a safe way to get all the benefits of NAD+ as the years go by. In fact, most studies on Niagen have been conducted using 1,000mg per day.

No matter what your age, there may be times when you stress your body more than usual. Like when you overeat, or drink too much. Maybe you’re very busy and don’t get enough sleep. Or you’ve been exposed to the sun for long periods of time. Under physiological stress, you may need more NAD+ in order to perform the same functions you once did at a lower amount. 1,000mg of NAD+ is safe (and recommended) for such stressful times.

Serious athletes and people who are highly active can also benefit from increased Niagen supplementation. Because NAD+ helps increase cellular energy production (ATP), it is a vital resource in helping muscles function before and during workouts, as well as aiding in post-workout repair and recovery.

Tru Niagen Immune

Whether you are taking 300mg or 1000mg, you can add Tru Niagen Immune to your arsenal and get extra immune support via recognizable forms of immune-boosting nutrients (vitamins D and C, zinc), plus a highly absorbable form of curcumin to further nourish your health. Tru Niagen Immune also contains 150mg of Niagen to help raise your NAD+ levels even further when they might be depleted most—like in the face of immune health challenges.

Consistency Is Everything

Niagen is a novel form of vitamin B3, but still holds the water-soluble properties of other vitamin B3s. Water-soluble vitamins require constant intake due to their inability to be stored in the body for long periods. Your body excretes these vitamins in urine, if not readily used. No matter which serving you decide is best for you, 300mg or 1,000mg, to consistently receive the healthy-aging benefits of Tru Niagen, it’s essential to take it every day.

And remember, while more is not always better, sometimes, it is.